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IKZF1

IKZF1 (IKAROS Family Zinc Finger 1): IKZF1 is a gene that encodes a zinc finger transcription factor crucial for the development and differentiation of immune cells, especially B cells. Mutations in IKZF1 are frequently observed in B-cell acute lymphoblastic leukemia (B-ALL), highlighting its vital role in hematopoiesis and immune regulation. Its interactions with other genes and its function in maintaining immune homeostasis make it a significant subject of study in both immunology and oncology.

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