NOTCH1
NOTCH1 (Notch Receptor 1): NOTCH1 is a crucial component of the Notch signalling pathway, which plays a significant role in cell fate determination, stem cell maintenance, and differentiation during both embryonic and adult tissue development. Dysregulation of NOTCH1 signalling is associated with various disorders, including several cancers such as T-cell acute lymphoblastic leukaemia, as well as developmental abnormalities. Its wide-ranging influence on cell proliferation and differentiation makes NOTCH1 a key focus in developmental biology and oncology research.
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