TMA / TMAO (Trimethylamine / Trimethylamine N-oxide)
Trimethylamine (TMA) is a metabolite produced by gut bacteria during the breakdown of choline, carnitine, and lecithin—nutrients commonly found in meat, eggs, and dairy. In the liver, TMA is converted into Trimethylamine N-oxide (TMAO), a compound that has been linked to cardiovascular risk in several studies. Elevated TMA/TMAO levels may reflect high microbial conversion activity in the gut, imbalanced microbiota, or a diet rich in animal-based products. While research is ongoing, high TMAO has been associated with inflammation and impaired cholesterol metabolism. Balanced gut flora and plant-forward diets may help maintain healthy TMAO levels.
Description
TMA is a compound produced by gut bacteria from certain dietary nutrients. The liver converts TMA into TMAO, which can enter circulation and affect vascular and metabolic processes.
Elevated TMAO has been linked to a higher risk of cardiovascular disease, as it can contribute to inflammation, oxidative stress, and impaired lipid metabolism.
Diets high in red meat, eggs, or dairy can increase TMAO levels, particularly in individuals with certain gut bacteria. Liver function also influences the conversion of TMA to TMAO.
Yes. Reducing intake of choline- and carnitine-rich foods, improving gut microbiome diversity, and increasing fiber intake may help lower TMAO production.
Not necessarily. Extremely low levels could indicate insufficient dietary precursors or microbial activity, but in most contexts, low or moderate TMAO is considered favorable for cardiovascular health.
Trusted by over 100.000+ customers
The home test was incredibly simple to use, with clear and easy-to-follow instructions. The results were precise and well-explained. I also appreciated the option to get my questions answered about the results.
Ramesh Kumar
I found the home test process seamless and hassle-free. The instructions were straightforward, and the results were presented in a very professional and clear manner. Having the chance to clarify my doubts made it even better.
Priya Sharma
Using the home test was a breeze. The directions were easy to understand, and the detailed results were shared promptly. It was comforting to know that I could ask questions about the results and get quick responses.
Amit Joshi
The home testing kit was simple to use, and the instructions were clear. The detailed report was very informative, and I felt reassured by the opportunity to discuss the results with a professional.
Meena Iyer
The home test was well-designed and came with clear, step-by-step instructions. The results were detailed and easy to interpret. I also appreciated being able to ask follow-up questions about my report.
Vikram Singh