NECTIN2

NECTIN2 (Nectin Cell Adhesion Molecule 2): NECTIN2, also called CD112, is a transmembrane protein belonging to the nectin family that facilitates cell-to-cell adhesion. It is predominantly expressed in epithelial and neuronal tissues and interacts with other nectins and receptors such as DNAM-1 (CD226), CD96, and TIGIT. NECTIN2 is crucial for the formation and maintenance of adherens junctions and synaptic connections, affecting cell migration, polarization, and synaptic transmission.

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