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ORC5

ORC5 (Origin Recognition Complex Subunit 5): ORC5 is a protein that forms part of the origin recognition complex, a crucial element in the initiation of DNA replication in eukaryotic cells. It plays a key role in ensuring precise DNA replication, which is essential for maintaining genomic integrity. Malfunction in ORC5 or the replication initiation process can result in genomic instability, a hallmark of cancer cells, and contribute to developmental disorders associated with impaired cell proliferation.

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