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PTPN22 (Protein Tyrosine Phosphatase, Non-Receptor Type 22): PTPN22 is an enzyme that reflects the regulation of immune responses in the body. It is a lymphoid-specific phosphatase that modulates T-cell receptor signaling and acts as a negative regulator of T-cell activation. PTPN22 is essential for maintaining immune tolerance and preventing autoimmune diseases. Genetic variations in PTPN22 have been associated with an increased risk of autoimmune diseases such as rheumatoid arthritis, type 1 diabetes, and systemic lupus erythematosus, highlighting its central role in immune regulation.

The GetTested DNA Immunity & Inflammation test reveals your genetic tendencies towards inflammation, autoimmune diseases, allergies, and infections. By examining genes linked to conditions like CRP (inflammation), psoriasis, and gluten sensitivity (celiac disease), as well as your response to common allergens and pathogens, it offers a deep dive into how your immune system functions.
₹ 16 110.00 INR
